Quantitative evaluation of whether the Nobel-Prize-winning COVID-19 vaccine actually saved millions of lives

Denis G. Rancourt,* PhD, and Joseph Hickey, PhD Correlation Research in the Public Interest

correlation-canada.org

This Correlation report is simultaneously posted on several websites, including:

https://denisrancourt.ca/

https://denisrancourt.substack.com/

All Correlation reports are here:

“Quantitative evaluation of
whether the Nobel-Prize-winning COVID-19 vaccine actually
saved millions of lives”

CORRELATION Research in the Public Interest, Brief Report, 08 October 2023.

https://correlation-canada.org/nobel-vaccine-and-all-cause-mortality/

Citation: Rancourt, D.G., and Hickey, J.,

1 Abstract


Fantastic statements that the Nobel-Prize-winning COVID-19 vaccines saved millions (and tens of millions) of lives are based on the theoretical scenarios of Watson et al. (2022), published in The Lancet Infectious Diseases. Watson et al. (2022) theoretically inferred massive mortality reductions distributed globally, occurring solely during vaccine rollouts. We calculated the quantitative consequences of Watson et al. (2022)’s low-value (14.4 million lives saved) theoretical scenario on all-cause mortality by time (by week or by month, 2020-2022) in 95 countries. Our calculations provide graphical proof that the theoretical proposals of Watson et al. (2022) are untenable, compared to measured all-cause mortality. Therefore, the characteristics of the COVID-19 vaccines (efficacies in preventing infection or serious illness, duration of protection, waning, etc.) and of COVID-19 spread input by Watson et al. (2022) must be invalid.

2 Context & Motivation


Leading legacy media have, in the last few days, asserted that the COVID-19 vaccine for which the 2023 Nobel prize in medicine was awarded saved “millions” and “tens of millions” of lives:

New York Times
Their work enabled potent Covid vaccines to be made in less than a year, averting tens of millions of deaths and helping the world recover from the worst pandemic in a century.” (2023-10-02)
https://www.nytimes.com/2023/10/02/health/nobel-prize-medicine.html


The Washington Post
It is the backbone of coronavirus vaccines that were developed in record time, providing a crucial shield of protection that helped save millions of lives and allowed people to reunite safely with loved ones.” (2023-10-02)
https://www.washingtonpost.com/science/2023/10/02/nobel-prize-medicine/


CBC
“’MRNA vaccines, together with other COVID-19 vaccines, have been administered over 13 billion times. Together they have saved millions of lives, prevented severe COVID-19, reduced the overall disease burden and enabled societies to open up again,’ said Thomas Perlmann, member of the Nobel Assembly at the Karolinska Institute.” (2023-10-02)
https://www.cbc.ca/news/health/nobel-prize-medicine-1.6984244

CNN
Rickard Sandberg, a member of the Nobel Prize in medicine committee, said, ‘mRNA vaccines together with other Covid-19 vaccines have been administered over 13 billion times. Together they have saved millions of lives, prevented severe Covid-19, reduced the overall disease burden and enabled societies to open up again.’” (2023-10-02)
https://www.cnn.com/2023/10/02/europe/nobel-prize-medicine-mrna-covid-vaccines-2023-intl-scn/index.html

Reuters
Pair lauded for helping save millions of lives” (2023-10-02)
https://www.reuters.com/business/healthcare-pharmaceuticals/kariko-weissman-win-medicine-nobel-covid-19-vaccine-work-2023-10-02/

Associated Press
Dr. Paul Hunter, a professor of medicine at Britain’s University of East Anglia, described the mRNA vaccines made by BioNTech-Pfizer and Moderna Inc. as a ‘game changer’ in shutting down the coronavirus pandemic, crediting the shots with saving millions of lives.” (2023-10-02)
https://apnews.com/article/nobel-prize-medicine-71306bd18785477f3a85a69caa6e09c9

Science News
In the year after their introduction, the shots are estimated to have saved nearly 20 million lives globally [citing Watson et al., 2022].” (2023-10-02)
https://www.sciencenews.org/article/nobel-prize-physiology-medicine-2023-mrna-vaccine-covid

The Nobel Prize
(Press Release, 2023-10-02)
The vaccines have saved millions of lives and prevented severe disease in many more, allowing societies to open and return to normal conditions.
https://www.nobelprize.org/prizes/medicine/2023/press-release/

To our knowledge: There is no known controlled randomized clinical trial with complete data demonstrating that the COVID-19 vaccines cause deaths to be averted. There is no controlled study showing that the COVID-19 vaccines save lives of individuals representative of any population or fragile group.

The Nobel Prize committee’s impressions and aligned media assertions are based on the modelling scenarios (“Global impact of the first year of COVID-19 vaccination: a mathematical modelling study”) reported by Watson et al. (2022) and published in the influential medical journal The Lancet Infectious Diseases.


In the abstract of their paper (which has been cited in scientific sources more than 700 times to date), Watson et al. (2022) state:


(Findings) Based on official reported COVID-19 deaths, we estimated that vaccinations prevented 14·4 million (95% credible interval [Crl] 13·7–15·9) deaths from COVID-19 in 185 countries and territories between Dec 8, 2020, and Dec 8, 2021. This estimate rose to 19·8 million (95% Crl 19·1– 20·4) deaths from COVID-19 averted when we used excess deaths as an estimate of the true extent of the pandemic, …

(Interpretation) COVID-19 vaccination has substantially altered the course of the pandemic, saving tens of millions of lives globally. …

(Funding) Schmidt Science Fellowship in partnership with the Rhodes Trust; WHO; UK Medical Research Council; Gavi, the Vaccine Alliance; Bill & Melinda Gates Foundation; National Institute for Health Research; and Community Jameel.


Here, we calculate the quantitative consequence of Watson et al.’s theoretical narrative on all-cause mortality by time in 95 countries to show that their results and the associated fantastic claims of millions of lives saved are highly improbable. Our calculations allow graphical demonstrations that the theoretical narrative of Watson et al. has no connection to actual mortality.

3 Data & Methods


The sources of the all-cause mortality and vaccination data by time are the same as in Rancourt et al. (2023) (their Figure 2).


The calculated all-cause mortality (or its excess) that corresponds to Watson et al. (2022)’s low-value scenario (14.4 million deaths prevented by COVID-19 vaccination in 185 countries, between 8 December 2020 and 8 December 2021), for each of 95 countries, is obtained as follows. Watson et al. (2022) provide individual evaluations for each of their 185 countries.


In general, in mathematical terms, the number of deaths averted (the outcome) is a convolution in time between vaccine administration (the intervention) and vaccine efficiency (including population susceptibility to infection) (the response).


Protection from COVID-19 vaccination (vaccine efficiency) is assumed, by Watson et al. (2022), to be imperfect and of limited duration. They take it to be modelled by an Erlang distribution. For simplicity, we apply a zero-to-constant rectangular response function of 180-day width, delayed by 14 days. These values are representative of mean (zero-to- constant) protection duration and delay of onset of maximum immunity, respectively. Our results are insensitive to these choices.


We thereby calculate the number of lives saved by time increment (week or month) and normalize the result to the number of lives saved reported for Watson et al. (2022)’s low-value scenario, between 8 December 2020 and 8 December 2021, for each of 95 countries.


In this way, we obtain the all-cause mortality by time that corresponds to the low-value scenario of Watson et al. (2022), for each of 95 countries. In other words, we calculate what total all-cause mortality would have been if the work of Watson et al. (2022) was a correct representation of reality and no COVID-19 vaccines were administered.

Likewise, we also express the results as excess all-cause mortality by time (week or month), for each of 95 countries.


Excess all-cause mortality by time (week or month) and its one-standard-deviation uncertainty are calculated as follows.
The excess all-cause mortality at a given time (week or month) is the difference (positive or negative) between the reported all-cause mortality for the given time and the expected all-cause mortality for the given time, which is ascertained from the historic all-cause mortality in a reference period immediately preceding the Covid period (prior to the 11 March 2020 World Health Organization declaration of a pandemic).

In practice, our reference period is 2015 through 2019. We least-squares fit a straight line to the same week or month in each of the five reference years as the week or month of interest, where the slope of this fitted line is constrained to always (for every week of month of interest) be equal to the slope of a least-squares fitted line to all of the all-cause mortality data (all weeks or months) in the full 5-year reference period, for each given country.


The thus obtained fitted line is used (by extrapolation) to predict the expected all-cause mortality. The one-standard-deviation (1σ) uncertainty in the expected all-cause mortality is estimated as sqrt(π/2) times the average magnitude of the 5 deviations in the 2015-2019 reference period, for each particular week or month of interest. This simple relation is exact in the limit of a large sampling number, for a normally distributed uncertainty.


Finally, the one-standard-deviation uncertainty of the excess mortality is the combined error that includes the 1σ uncertainty in the expected value and the independent statistical (1σ) error in the all-cause mortality (sqrt(N)).

4 Results & Discussion


Our results for all 95 countries, both in terms of all-cause mortality itself and excess all-cause mortality, are given in Appendix A.
Our calculations for the USA are shown in two panels in Figure 1, as follows.

In all the mortality figures (for all 95 countries and for both raw and excess all-cause mortalities), “continued” (red-dashed line) simply means that the convolution calculation is continued beyond the period (8 December 2020 to 8 December 2021) corresponding to the Watson et al. (2022) simulation, using the same convolution parameters. In each of the mortality figures, the area between the red-solid and blue curves, in the period from 8 December 2020 to 8 December 2021, is equal to the low-value scenario number of lives saved reported by Watson et al. (2023) for the specific country.


In the USA, there are unprecedented peaks in all-cause mortality (and excess all-cause mortality) in 2020, 2021, and 2022 (Figure 1). These features and their epidemiological characteristics have been discussed extensively elsewhere (Rancourt et al., 2021, 2022a). March 11, 2020 is the date at which the World Health Organization (WHO) declared a pandemic.


If we believe that the low-value scenario of Watson et al. (2022) is a correct representation of reality for the USA, then Figure 1 shows that we have to believe that a massive and more-than-unprecedented national excess all-cause mortality — doubling the all-cause mortality by week for at least one year — would have occurred precisely in the period when the COVID-19 vaccines were mostly rolled out, and not before, had the vaccines not been rolled out.
This would be a remarkable coincidence, following several presumed waves of infection, and past one year of declared pandemic, in actual measured circumstances in which there is no visible decrease in all-cause mortality that is temporally associated with the rollouts. In fact, there are additional peaks and sustained excess all-cause mortality (Figure 1).


Let us move to Canada, which shares a large land border and intense trade relations with the USA. Our calculations for Canada are shown in two panels in Figure 2.

From this calculation for Canada (Figure 2), we see that the Watson et al. (2022) low-value scenario is palpably absurd.


On the scale of these plots (Figure 2), essentially nothing happened following the WHO declaration of a pandemic, yet the low-value scenario of Watson et al. (2022) would have us believe that a disproportionate and massive national excess all-cause mortality — tripling the all-cause mortality by week for approximately one year — would have occurred precisely in the period when the COVID-19 vaccines were mostly rolled out, and not before, had the vaccines not been rolled out.
This, again, would be a remarkable coincidence, following presumed waves of infection, and past one year of declared pandemic, in measured circumstances in which not only is there no visible decrease in actual all-cause mortality that is temporally associated with the rollouts, but the opposite is apparent, with excess mortality proportionately accompanying rollouts (Figure 2, bottom panel).


Similarly absurd results, citing Watson et al. (2022), and not solely for vaccination, have been proposed previously for Canada (Ogden et al., 2022), and have been critiqued (Rancourt et al., 2022b).


Crossing the Atlantic to Europe, results for a consolidated group of 31 European countries, chosen because their data is by week, are as follows.


Figure 3 shows a map of the 31 countries: Austria, Belgium, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, and United Kingdom.

Finland (Figure 5) and Norway (Figure 6) have remarkably similar mortality behaviours to each other. Both demonstrate, again, that the Watson et al. (2022) low value scenario is absurd, compared to directly observed all-cause mortality.
On the scale of these plots (Figure 5, Figure 6), nothing detectably happened following the WHO declaration of a pandemic, yet the low-value scenario of Watson et al. (2022) would have us believe that a disproportionate and massive national excess all-cause mortality — doubling the all-cause mortality by week for approximately one year — would have occurred precisely in the period when the COVID-19 vaccines were mostly rolled out, and not before, had the vaccines not been rolled out.


This remarkable coincidence (which is present for virtually every country, above and Appendix A) would occur:

  1. following presumed waves of infection (which, here, in Finland and Norway, did not cause any detectable excess all-cause mortality),
  2. past one year of declared pandemic, and
  3. in actual measured circumstances in which not only is there no visible decrease in all-cause mortality that is temporally associated with the rollouts but the opposite is true, with gradual rises in excess all-cause mortality during the rollouts (Figure 5, Figure 6, bottom panels).

Finally, let us examine two particularly striking examples, on different continents, each one sufficient to disprove the validity of Watson et al. (2022)’s low-value scenario (and their high-value scenario of 19.8 million saved lives). Figure 7 shows the case of Qatar, and Figure 8 shows the case of Singapore.

For both Qatar (Figure 7) and Singapore (Figure 8), the results are staggering.


Here (Figure 7, Figure 8), the low-value scenario (14.4 million saved lives) of Watson et al. (2022) corresponds to an approximately 10-fold increase in all-cause mortality by month, lasting 3 months or more in 2021, whereas both countries, on this scale, have virtually no change in measured all-cause mortality, across the declared pandemic (2020-2023), compared to the historic values (< 2020).

In all such cases, including all the examples described above, one has to wonder how it is possible that massive excess all-cause mortality would have occurred, solely during vaccine rollouts, and that the COVID-19 vaccination would have reduced this mortality down to precisely the pre-declared-pandemic values or pre-COVID-19-vaccination values, and not to some intermediate value of mortality, across at least one year of vaccination. This extraordinary coincidence essentially occurs in most of 95 countries (Appendix A).


In fact, the said coincidence is palpably so improbable that it should, without hesitation, be qualified as impossible. A single such example in a single country is sufficient to invalidate the exercise of Watson et al. (2022), and the example is repeated for 95 countries (Appendix A).

5 Conclusion


We calculated the quantitative consequences of Watson et al. (2022)’s theoretical scenario on all-cause mortality by time (by week or by month, 2020-2022) in 95 countries.


Our calculations provide graphical proof that the theoretical proposals of Watson et al. (2022) — corresponding globally to 14.4 or 19.8 million lives saved by COVID-19 vaccination — are untenable, and are not even partially correct.
There is no evidence in actual all-cause mortality data that the COVID-19 vaccine rollouts had any beneficial effect. In fact, the contrary is apparent.

Importantly, this means that the characteristics of the COVID-19 vaccines (efficacies in preventing infection or serious illness, duration of protection, waning, etc.) and of COVID-19 spread input by Watson et al. (2022) must be invalid.

In other words, the COVID-19 vaccine efficacies and COVID-19 spread implemented in the Watson et al. (2022) scenarios predict massive mortality reductions on the global scale, which are incompatible with reality.


The following additional consequences and criticisms follow from our demonstration:

  • Theoretical modellers that apply their trade to epidemiological problems are
    entirely able to misdirect themselves, without validating their results by
    comparisons to hard data.
  • The legacy-journal peer review system has failed remarkably in the case of
    Watson et al. (2022), which suggests scientific illiteracy among reviewers and
    editors.
  • Scientists, editors, lawmakers and Nobel Prize committee members are
    susceptible to accepting self-serving fantastic claims, without question.
  • Leading legacy media have made and repeated absurd statements about Nobel-
    Prize COVID-19 vaccines having saved millions of lives, without any significant verification.

6 References


Ogden NH, Turgeon P, Fazil A, Clark J, Gabriele-Rivet V, Tam T, Ng V. (2022) „Counterfactuals of effects of vaccination and public health measures on COVID-19 cases in Canada: What could have happened?“ Canada Communicable Disease Report (CCDR) 2022;48(7/8):292–302. https://doi.org/10.14745/ccdr.v48i78a01


Rancourt, D.G., Baudin, M. and Mercier, J. (2021) /// Nature of the COVID-era public health disaster in the USA, from all-cause mortality and socio-geo-economic and climatic data. /// Research Gate (25 Ocbtober 2021)
/// http://dx.doi.org/10.13140/RG.2.2.11570.32962

Rancourt, D.G., Baudin, M. and Mercier, J. (2022a) /// COVID-Period Mass Vaccination Campaign and Public Health Disaster in the USA: From age/state-resolved all-cause mortality by time, age-resolved vaccine delivery by time, and socio-geo-economic data /// Research Gate (2 August 2022) /// http://dx.doi.org/10.13140/RG.2.2.12688.28164 /// Also available at: https://vixra.org/abs/2208.0023


Rancourt, D.G., Baudin, M. and Mercier, J. (2022b) /// Proof that Canada’s COVID-19 mortality statistics are incorrect. /// Correlation Research in the Public Interest, 5 October 2022 /// https://correlation-canada.org/report-proof-that-canadas-covid-19-mortality-statistics-are-incorrect/


Rancourt, D.G., Baudin, M., Hickey, J., Mercier, J. (2023) “COVID-19 vaccine- associated mortality in the Southern Hemisphere”. CORRELATION Research in the Public Interest, Report, 17 September 2023. https://correlation-canada.org/covid-19-vaccine-associated-mortality-in-the-Southern-Hemisphere/


Watson OJ, Barnsley G, Toor J, Hogan AB, Winskill P, Ghani AC. (2022) “Global impact of the first year of COVID-19 vaccination: a mathematical modelling study”. Lancet Infect Dis. 2022 Sep;22(9):1293-1302. doi: 10.1016/S1473-3099(22)00320-6. Epub 2022 Jun 23. Erratum in: Lancet Infect Dis. 2023 Oct;23(10):e400. PMID: 35753318; PMCID: PMC9225255. https://doi.org/10.1016/s1473-3099(22)00320-6

Read the rest
of this paper for yourself:

(from page 20-115)

https://correlation-canada.org/wp-content/uploads/2023/10/2023-10-08-Correlation-Whether-Nobel-vaccine-saved-millions-of-lives.pdf#page13

Scottish Covid Inquiry

Scottish Health Secretary Jeane Freeman gives evidence at the UK COVID-19 Inquiry Scotland suffered 5,000 deaths in Care Homes during lockdown 2,500 more deaths than average across the 10 week lockdown from 23rd March 2020 to 29th May 2020 Jeane Freeman letter 13/3/2020 https://scottishcare.org/wp-content/u… Link to UK Inquiry Hearings https://covid19.public-inquiry.uk/hea… National Records of Scotland (pandemic death statistics) https://www.nrscotland.gov.uk/statist… Time Stamp 0:00 Regret for the rest of my life 0:44 5,000 Care Home Deaths 1:24 Denied Hospital Care 3:45 Care Home Guidance 4:35 Hospital transfers 6:49 On your own 7:07 Dr Macaskill 7:58 End Credits

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